Apolipoprotein B100 autoimmunity and atherosclerosis – disease mechanisms and therapeutic potential

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Apolipoprotein B100 autoimmunity and atherosclerosis - disease mechanisms and therapeutic potential.

PURPOSE OF REVIEW Adaptive immune responses have been shown to play an important role in the atherosclerotic disease process and both pathogenic and protective immunity has been identified. Apolipoprotein (apo) B100 appears to be a key antigen and novel therapies modulating immune responses against apo B100 have shown promising results in experimental models. This review will discuss recent dev...

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ژورنال

عنوان ژورنال: Current Opinion in Lipidology

سال: 2012

ISSN: 0957-9672

DOI: 10.1097/mol.0b013e328356ec7c